Lupus 2014; 23: 225–35 Fischer-Betz R, Schneider M, Kommission Pharmakotherapie der DGRh: Empfehlungen zum Einsatz von Belimumab beim systemischen Lupus erythematodes.
A problem based approach]. Systemic Lupus Erythematosus (SLE), also known as lupus, is a disease of the immune system, which is estimated to affect more than 20,000 people in Australia and New Zealand. : Morbidity and mortality in systemic lupus erythematosus during a 10-year period: a comparison of early and late manifestations in a cohort of 1,000 patients. Berlin: Springer-Verlag 2004; 45–52.Gilliam JN, Sontheimer RD: Distinctive cutaneous subsets in the spectrum of lupus erythematosus. (last accessed on 19 March 2015).Barsalou J, Levy DM, Silverman ED: An update on childhood-onset systemic lupus erythematosus. Elsevier Science Systemic lupus erythematosus (SLE) is a complex autoim-mune disease with variable clinical features (1,2). Systemic lupus erythematosus diagnosis and management Bernard Thong 1 Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore, Republic of Singapore. Medicine (Baltimore) 1993; 72: 113–24 Fischer-Betz R, Herzer P, Schneider M: Systemischer Lupus erythematodes. : European League Against Rheumatism recommendations for monitoring patients with systemic lupus erythematosus in clinical practice and in observational studies. : Protective effect of hydroxychloroquine on renal damage in patients with lupus nephritis: LXV, data from a multiethnic US cohort. Manche sind für die Beurteilung der Krankheit bei Kindern besser geeignet als andere. And unlike some other diseases, it cannot be diagnosed with a single lab test. In: Korting H, Callies R, Reusch M, Schlaeger M, Sterry W (eds. Anders; Praxis für Innere Medizin – Rheumatologie, München: Prof. Dr. med. Arch Dermatol 2009; 145: 244–8.Sardy M, Ruzicka T, Kuhn A: Topical calcineurin inhibitors in cutaneous lupus erythematosus. In: Kuhn A, Lehmann P, Ruzicka T (eds. Im Gegensatz dazu steigen anti-dsDNA Antikörper häufig schon mehrere Monate vor einem Schub an, parallel zu einem Abfall von Komplementfaktoren (Die weitere Diagnostik des SLE erfolgt symptomorientiert unter Einbindung von Spezialisten der entsprechenden Fachdisziplin. 2006 Mar;2(3):145-52. doi: 10.1038/ncprheum0116.Ganugula R, Arora M, Zou D, Agarwal SK, Mohan C, Kumar MNVR.Sci Adv. This complex clinical presentation and pathogenesis makes SLE a difficult disease to grasp and define. Systemic lupus erythematosus (SLE) is a worldwide chronic autoimmune disease which may affect every organ and tissue. Curr Opin Rheumatol 2013; 25: 616–22 Kuhn A, Ruland V, Bonsmann G: Cutaneous lupus erythematosus: update of therapeutic options part I. J Am Acad Dermatol 2011; 65: e179–93 Marmor MF, Kellner U, Lai TY, Lyons JS, Mieler WF: Revised recommendations on screening for chloroquine and hydroxychloroquine retinopathy. J Prenat Med 2010; 4: 67–73.Clowse ME, Magder L, Witter F, Petri M: Hydroxychloroquine in lupus pregnancy. Diagnostik abhängig von der OrganbeteiligungTherapieempfehlungen bei systemischem Lupus erythematodes mit aktiver Organbeteiligung am Beispiel der proliferativen Lupusnephritis Cervera R, Khamashta MA, Font J, et al. Lupus 2009; 18: 104–5.Interdisziplinäres Zentrum Klinische Studien (IZKS), Universitätsmedizin Mainz: Prof. Dr. med. Medicine (Baltimore) 1999; 78: 167–75.Danza A, Ruiz-Irastorza G: Infection risk in systemic lupus erythematosus patients: susceptibility factors and preventive strategies. 2020 May 13;18(2):1559325820926764. doi: 10.1177/1559325820926764. Bei der Diagnostik des Lupus werden verschiedene Parameter …

Here, we review the diagnostic approach as well as the etiopathogenetic rationale and clinical evidence for the management of SLE. Schneider erhielt Honorare für eine Beratertätigkeit von GSK, UCB, Lilly und Astra-Zeneca. Arthritis Rheum 2010; 62: 211–21 Bertsias G, Cervera R, Boumpas D: Systemic lupus erythematosus: pathogenesis and clinical features.

Bei kutanen Manifestationen sollte zur Abgrenzung von Differenzialdiagnosen ein dermatologisches Konsil mit Biopsie aus Haut- und/oder Mundschleimhautveränderungen (Histologie/Immunfluoreszenz) durchgeführt werden (Zur Erfassung der Aktivität des SLE wurden Scores (SLEDAI, SLAM, BILAG, ECLAM) entwickelt, die im Wesentlichen klinische Befunde und Laborparameter beinhalten (Die Behandlung des SLE basiert auf wenigen randomisierten kontrollierten Studien, auch sind die Einschlusskriterien bei heterogener Ausprägung der Erkrankung und niedrigen Patientenzahlen nicht einheitlich.

doi: 10.1093/rheumatology/kew417.Expert Rev Clin Pharmacol. ): EULAR textbook on rheumatic diseases. Arthritis Rheum 1982; 25: 1271–7.Jimenez S, Cervera R, Ingelmo M, Font J: The epidemiology of cutaneous lupus erythematosus.

Z Rheumatol 2011; 70: 480–5 Cervera R, Khamashta MA, Font J, et al. Copyright © 2018 Elsevier Ltd. All rights reserved.
Heidelberg, Berlin, New York: Springer Verlag 2004; 53–9.Kleinert S, Feuchtenberger M, Tony HP: Systemischer Lupus erythematodes. In this disease, the immune system of the body mistakenly attacks healthy tissue. eCollection 2020 Jun.Xing ZX, Yu K, Yang H, Liu GY, Chen N, Wang Y, Chen M.World J Clin Cases. SLE manifesta-tions are associated with multiple autoantibodies, ensuing immune complex formation and deposition, and other immune processes (2,3).

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